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Dendritic Cell-Based Vaccination in Cancer: Therapeutic Implications Emerging from Murine Models
Dendritic cells (DCs) play a pivotal role in the orchestration of immune responses, and are thus key targets in cancer vaccine design. Since the 2010 FDA approval of the first cancer DC-based vaccine (Sipuleucel-T), there has been a surge of interest in exploiting these cells as a therapeutic option...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438595/ https://www.ncbi.nlm.nih.gov/pubmed/26042126 http://dx.doi.org/10.3389/fimmu.2015.00243 |