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Structural Insights into Substrate Specificity of Feruloyl-CoA 6’-Hydroxylase from Arabidopsis thaliana

Coumarins belong to an important class of plant secondary metabolites. Feruloyl-CoA 6’-hydroxylase (F6’H), a 2-oxoglutarate dependent dioxygenase (2OGD), catalyzes a pivotal step in the biosynthesis of a simple coumarin scopoletin. In this study, we determined the 3-dimensional structure of the F6’H...

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Detalles Bibliográficos
Autores principales: Sun, Xinxiao, Zhou, Dayong, Kandavelu, Palani, Zhang, Hua, Yuan, Qipeng, Wang, Bi-Cheng, Rose, John, Yan, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438608/
https://www.ncbi.nlm.nih.gov/pubmed/25993561
http://dx.doi.org/10.1038/srep10355