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The effect of lysophosphatidic acid during in vitro maturation of bovine cumulus–oocyte complexes: cumulus expansion, glucose metabolism and expression of genes involved in the ovulatory cascade, oocyte and blastocyst competence

BACKGROUND: In the cow, lysophosphatidic acid (LPA) acts as an auto-/paracrine factor, through its receptors LPAR1-4, on oocytes and cumulus cells during in vitro maturation (IVM). The aim of the present work was to determine the effect of LPA during IVM of bovine oocytes on: 1) oocyte maturation; 2...

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Detalles Bibliográficos
Autores principales: Boruszewska, Dorota, Sinderewicz, Emilia, Kowalczyk-Zieba, Ilona, Grycmacher, Katarzyna, Woclawek-Potocka, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438640/
https://www.ncbi.nlm.nih.gov/pubmed/25981539
http://dx.doi.org/10.1186/s12958-015-0044-x