Innate lymphotoxin receptor mediated signaling promotes HSV-1 associated neuroinflammation and viral replication

Host anti-viral innate immunity plays important roles in the defense against HSV-1 infection. In this study, we find an unexpected role for innate LT/LIGHT signaling in promoting HSV-1 replication and virus induced inflammation in immunocompromised mice. Using a model of footpad HSV-1 infection in R...

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Detalles Bibliográficos
Autores principales: Liang, Yong, Yang, Kaiting, Guo, Jingya, Wroblewska, Joanna, Fu, Yang-Xin, Peng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438665/
https://www.ncbi.nlm.nih.gov/pubmed/25993659
http://dx.doi.org/10.1038/srep10406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438665/
https://www.ncbi.nlm.nih.gov/pubmed/25993659
http://dx.doi.org/10.1038/srep10406

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