Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression

How cells in developing organisms interpret the quantitative information contained in morphogen gradients is an open question. Here we address this question using a novel integrative approach that combines quantitative measurements of morphogen-induced gene expression at single-mRNA resolution with...

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Detalles Bibliográficos
Autores principales: van Zon, Jeroen Sebastiaan, Kienle, Simone, Huelsz-Prince, Guizela, Barkoulas, Michalis, van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438782/
https://www.ncbi.nlm.nih.gov/pubmed/25958991
http://dx.doi.org/10.1038/ncomms8053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438782/
https://www.ncbi.nlm.nih.gov/pubmed/25958991
http://dx.doi.org/10.1038/ncomms8053

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