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Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression
How cells in developing organisms interpret the quantitative information contained in morphogen gradients is an open question. Here we address this question using a novel integrative approach that combines quantitative measurements of morphogen-induced gene expression at single-mRNA resolution with...
Autores principales: | van Zon, Jeroen Sebastiaan, Kienle, Simone, Huelsz-Prince, Guizela, Barkoulas, Michalis, van Oudenaarden, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438782/ https://www.ncbi.nlm.nih.gov/pubmed/25958991 http://dx.doi.org/10.1038/ncomms8053 |
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