Crystal structure of 5-{4′-[(2-{2-[2-(2-ammonio­eth­oxy)eth­oxy]eth­oxy}eth­yl)carbamo­yl]-4-meth­oxy-[1,1′-biphen­yl]-3-yl}-3-oxo-1,2,5-thia­diazo­lidin-2-ide 1,1-dioxide: a potential inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B)

The title compound, C(24)H(32)N(4)O(8)S, (I), crystallizes as a zwitterion. The terminal amine N atom of the [(2-{2-[2-(2-ammonio­eth­oxy)eth­oxy]eth­oxy}eth­yl)carbamo­yl] side chain is protonated, while the 1,2,5-thia­diazo­lidin-3-one 1,1-dioxide N atom is deprotonated. The side chain is turned o...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruddraraju, Kasi Viswanatharaju, Hillebrand, Roman, Barnes, Charles L., Gates, Kent S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438830/
https://www.ncbi.nlm.nih.gov/pubmed/26029383
http://dx.doi.org/10.1107/S2056989015003850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438830/
https://www.ncbi.nlm.nih.gov/pubmed/26029383
http://dx.doi.org/10.1107/S2056989015003850

Ejemplares similares