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Immune-enhancing effect of nano-DNA vaccine encoding a gene of the prME protein of Japanese encephalitis virus and BALB/c mouse granulocyte-macrophage colony-stimulating factor

Plasmid-encoded granulocyte-macrophage colony-stimulating factor (GM-CSF) is an adjuvant for genetic vaccines; however, how GM-CSF enhances immunogenicity remains to be elucidated. In the present study, it was demonstrated that injection of a plasmid encoding the premembrane (prM) and envelope (E) p...

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Detalles Bibliográficos
Autores principales: ZHAI, YONGZHEN, ZHOU, YAN, LI, XIMEI, FENG, GUOHE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438877/
https://www.ncbi.nlm.nih.gov/pubmed/25738258
http://dx.doi.org/10.3892/mmr.2015.3419