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Estrogen receptor α mediates the effects of notoginsenoside R1 on endotoxin-induced inflammatory and apoptotic responses in H9c2 cardiomyocytes

Estrogen receptors (ERs) are important for preventing endotoxin-induced myocardial dysfunction. Therefore, plant-derived phytoestrogens, which target ERs may also affect endotoxin-induced toxicity in cardiomyocytes. Our previous study revealed that notoginsenoside-R1 (NG-R1), a predominant phytoestr...

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Detalles Bibliográficos
Autores principales: ZHONG, LEI, ZHOU, XING-LU, LIU, YAN-SONG, WANG, YI-MIN, MA, FEI, GUO, BAO-LIANG, YAN, ZHAO-QI, ZHANG, QING-YUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438911/
https://www.ncbi.nlm.nih.gov/pubmed/25738436
http://dx.doi.org/10.3892/mmr.2015.3394