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Chemoresistance to doxorubicin induces epithelial-mesenchymal transition via upregulation of transforming growth factor β signaling in HCT116 colon cancer cells

Doxorubicin (Dox) is a commonly used chemotherapeutic drug in human colon cancer. However, it becomes increasingly ineffective with tumor progression, the underlying mechanism of which remains to be elucidated. Emerging evidence has led to the identification of an association between chemoresistance...

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Detalles Bibliográficos
Autores principales: LI, JINPENG, LIU, HAO, YU, JIEPING, YU, HONGGANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438913/
https://www.ncbi.nlm.nih.gov/pubmed/25684678
http://dx.doi.org/10.3892/mmr.2015.3356