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All-trans-retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by downregulating p53 expression

Despite the well-established role of all-trans-retinoic acid (ATRA) in congenital clubfoot (CCF)-like deformities in in vivo models, the essential cellular and molecular targets and the signaling mechanisms for ATRA-induced CCF-like deformities remain to be elucidated. Recent studies have demonstrat...

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Detalles Bibliográficos
Autores principales: ZHANG, TAO-GEN, LI, XUE-DONG, YU, GUO-YONG, XIE, PENG, WANG, YUN-GUO, LIU, ZHAO-YONG, HONG, QUAN, LIU, DE-ZHONG, DU, SHI-XIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438916/
https://www.ncbi.nlm.nih.gov/pubmed/25738595
http://dx.doi.org/10.3892/mmr.2015.3423