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Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling

The differentiation of pluripotent mesenchymal stem cells to mature osteoblasts is crucial for the maintenance of the adult skeleton. In rheumatic arthritis, osteoblast differentiation is impaired by the overproduction of cytokine tumor necrosis factor (TNF)-α. It has been demonstrated that TNF-α is...

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Detalles Bibliográficos
Autores principales: WANG, GUANGYE, ZHANG, XIAOHAI, YU, BAOQING, REN, KE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438943/
https://www.ncbi.nlm.nih.gov/pubmed/25816130
http://dx.doi.org/10.3892/mmr.2015.3524