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Calcitriol ameliorates renal damage in a pre-established proteinuria model

Proteinuria is critical in the tubulointerstitial changes that ultimately lead to renal insufficiency. Increased protein filtration has direct toxic effects on tubular epithelial cells, leading to epithelial mesenchymal transition (EMT) to a myofibroblast phenotype. Angiotensin II and transforming g...

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Detalles Bibliográficos
Autores principales: MAQUIGUSSA, EDGAR, ARNONI, CARINE P, PEREIRA, LUCIANA G, BOIM, MIRIAN A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438961/
https://www.ncbi.nlm.nih.gov/pubmed/25823676
http://dx.doi.org/10.3892/mmr.2015.3555