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Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo

Axonal regeneration after injury requires the coordinated expression of genes in injured neurons. We previously showed that either reducing expression or blocking function of the transcriptional repressor NFIL3 activates transcription of regeneration-associated genes Arg1 and Gap43 and strongly prom...

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Detalles Bibliográficos
Autores principales: van der Kallen, Loek R., Eggers, Ruben, Ehlert, Erich M., Verhaagen, Joost, Smit, August B., van Kesteren, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438979/
https://www.ncbi.nlm.nih.gov/pubmed/25993115
http://dx.doi.org/10.1371/journal.pone.0127163