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Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo
Axonal regeneration after injury requires the coordinated expression of genes in injured neurons. We previously showed that either reducing expression or blocking function of the transcriptional repressor NFIL3 activates transcription of regeneration-associated genes Arg1 and Gap43 and strongly prom...
Autores principales: | van der Kallen, Loek R., Eggers, Ruben, Ehlert, Erich M., Verhaagen, Joost, Smit, August B., van Kesteren, Ronald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438979/ https://www.ncbi.nlm.nih.gov/pubmed/25993115 http://dx.doi.org/10.1371/journal.pone.0127163 |
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