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Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display

The identification of marker molecules specific for blood and lymphatic endothelium may provide new diagnostic tools and identify new targets for therapy of immune, microvascular and cancerous diseases. Here, we used a phage display library expressing human randomized single-chain Fv (scFv) antibodi...

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Detalles Bibliográficos
Autores principales: Keller, Thomas, Kalt, Romana, Raab, Ingrid, Schachner, Helga, Mayrhofer, Corina, Kerjaschki, Dontscho, Hantusch, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439027/
https://www.ncbi.nlm.nih.gov/pubmed/25993332
http://dx.doi.org/10.1371/journal.pone.0127169