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Ceramide as a Mediator of Non-Alcoholic Fatty Liver Disease and Associated Atherosclerosis

Cardiovascular disease (CVD) is a serious comorbidity in nonalcoholic fatty liver disease (NAFLD). Since plasma ceramides are increased in NAFLD and sphingomyelin, a ceramide metabolite, is an independent risk factor for CVD, the role of ceramides in dyslipidemia was assessed using LDLR-/- mice, a d...

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Detalles Bibliográficos
Autores principales: Kasumov, Takhar, Li, Ling, Li, Min, Gulshan, Kailash, Kirwan, John P., Liu, Xiuli, Previs, Stephen, Willard, Belinda, Smith, Jonathan D., McCullough, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439060/
https://www.ncbi.nlm.nih.gov/pubmed/25993337
http://dx.doi.org/10.1371/journal.pone.0126910