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Ceramide as a Mediator of Non-Alcoholic Fatty Liver Disease and Associated Atherosclerosis
Cardiovascular disease (CVD) is a serious comorbidity in nonalcoholic fatty liver disease (NAFLD). Since plasma ceramides are increased in NAFLD and sphingomyelin, a ceramide metabolite, is an independent risk factor for CVD, the role of ceramides in dyslipidemia was assessed using LDLR-/- mice, a d...
Autores principales: | Kasumov, Takhar, Li, Ling, Li, Min, Gulshan, Kailash, Kirwan, John P., Liu, Xiuli, Previs, Stephen, Willard, Belinda, Smith, Jonathan D., McCullough, Arthur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439060/ https://www.ncbi.nlm.nih.gov/pubmed/25993337 http://dx.doi.org/10.1371/journal.pone.0126910 |
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