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Binding of the Antagonist Caffeine to the Human Adenosine Receptor hA(2A)R in Nearly Physiological Conditions
Lipid composition may significantly affect membrane proteins function, yet its impact on the protein structural determinants is not well understood. Here we present a comparative molecular dynamics (MD) study of the human adenosine receptor type 2A (hA(2A)R) in complex with caffeine—a system of high...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439127/ https://www.ncbi.nlm.nih.gov/pubmed/25992797 http://dx.doi.org/10.1371/journal.pone.0126833 |