Reciprocal Regulation of C-Maf Tyrosine Phosphorylation by Tec and Ptpn22

C-Maf plays an important role in regulating cytokine production in T(H) cells. Its transactivation of IL-4 is optimized by phosphorylation at Tyr21, Tyr92, and Tyr131. However, the molecular mechanism regulating its tyrosine phosphorylation remains unknown. In this study, we demonstrate that Tec kin...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chih-Chun, Lai, Chen-Yen, Yen, Wei-Feng, Lin, Yu-Hsien, Chang, Hui-Hsin, Tai, Tzong-Shyuan, Lu, Yu-Jung, Tsao, Hsiao-Wei, Ho, I-Cheng, Miaw, Shi-Chuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439128/
https://www.ncbi.nlm.nih.gov/pubmed/25993510
http://dx.doi.org/10.1371/journal.pone.0127617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439128/
https://www.ncbi.nlm.nih.gov/pubmed/25993510
http://dx.doi.org/10.1371/journal.pone.0127617

Ejemplares similares