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Reciprocal Regulation of C-Maf Tyrosine Phosphorylation by Tec and Ptpn22
C-Maf plays an important role in regulating cytokine production in T(H) cells. Its transactivation of IL-4 is optimized by phosphorylation at Tyr21, Tyr92, and Tyr131. However, the molecular mechanism regulating its tyrosine phosphorylation remains unknown. In this study, we demonstrate that Tec kin...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439128/ https://www.ncbi.nlm.nih.gov/pubmed/25993510 http://dx.doi.org/10.1371/journal.pone.0127617 |