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Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients

Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells, which increase in cancer patients. The molecular mechanism behind their generation and function is unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer, the presence and relevanc...

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Detalles Bibliográficos
Autores principales: Bergenfelz, Caroline, Larsson, Anna-Maria, von Stedingk, Kristoffer, Gruvberger-Saal, Sofia, Aaltonen, Kristina, Jansson, Sara, Jernström, Helena, Janols, Helena, Wullt, Marlene, Bredberg, Anders, Rydén, Lisa, Leandersson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439153/
https://www.ncbi.nlm.nih.gov/pubmed/25992611
http://dx.doi.org/10.1371/journal.pone.0127028