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Innate lymphoid cell development requires TOX-dependent generation of a common ILC progenitor

Diverse innate lymphoid cell (ILC) subtypes have been defined, based on effector function and transcription factor expression. ILCs derive from common lymphoid progenitors, although the transcriptional pathways leading to ILC lineage specification remain poorly characterized. Here we demonstrate tha...

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Detalles Bibliográficos
Autores principales: Seehus, Corey R., Aliahmad, Parinaz, de la Torre, Brian, Iliev, Iliyan D., Spurka, Lindsay, Funari, Vincent A., Kaye, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439271/
https://www.ncbi.nlm.nih.gov/pubmed/25915732
http://dx.doi.org/10.1038/ni.3168