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Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis

Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166), is expressed on osteoblasts (OB) and hematopoietic stem cells (HSC) residing in the hematopoietic niche, and may have important regulatory roles in bone formation. Because HSC numbers are reduced 77% in CD166(-/-) mice, we hypothesized that c...

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Detalles Bibliográficos
Autores principales: Hooker, R.A., Chitteti, B.R., Egan, P.H., Cheng, Y-H., Himes, E.R., Meijome, T., Srour, E.F., Fuchs, R.K., Kacena, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society of Musculoskeletal and Neuronal Interactions 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439374/
https://www.ncbi.nlm.nih.gov/pubmed/25730656