BRCA1, BRCA2, PALB2, and CDKN2A Mutations in Familial Pancreatic Cancer (FPC): A PACGENE Study

PURPOSE: Familial Pancreatic Cancer (FPC) kindreds contain at least two affected first-degree relatives (FDR). Comprehensive data are needed to assist clinical risk assessment and genetic testing. METHODS: Germline DNA samples from 727 unrelated probands with positive family history (521 met criteri...

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Detalles Bibliográficos
Autores principales: Zhen, David B., Rabe, Kari G., Gallinger, Steven, Syngal, Sapna, Schwartz, Ann G., Goggins, Michael G., Hruban, Ralph H., Cote, Michele L., McWilliams, Robert R., Roberts, Nicholas J., Cannon-Albright, Lisa A., Li, Donghui, Moyes, Kelsey, Wenstrup, Richard J., Hartman, Anne-Renee, Seminara, Daniela, Klein, Alison P., Petersen, Gloria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439391/
https://www.ncbi.nlm.nih.gov/pubmed/25356972
http://dx.doi.org/10.1038/gim.2014.153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439391/
https://www.ncbi.nlm.nih.gov/pubmed/25356972
http://dx.doi.org/10.1038/gim.2014.153

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