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Inclusion complexes of trihexyphenidyl with natural and modified cyclodextrins
The solubility of trihexyphenidyl (Thp) was improved by its combination with β-cyclodextrin (β−CD) and modified β-CDs. The solubility of Thp was found to be increased in the presence of β-CD, hydroxypropyl-β-cyclodextrin (HP-β-CD), methyl-β-cyclodextrin (Me-β-CD) and sulfobutylether-β-cyclodextrin (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439407/ https://www.ncbi.nlm.nih.gov/pubmed/26020020 http://dx.doi.org/10.1186/s40064-015-0986-7 |