Novel 3′-Processing Integrase Activity Assay by Real-Time PCR for Screening and Identification of HIV-1 Integrase Inhibitors

The 3′-end processing (3′P) of each viral long terminal repeat (LTR) during human immunodeficiency virus type-1 (HIV-1) integration is a vital step in the HIV life cycle. Blocking the 3′P using 3′P inhibitor has recently become an attractive strategy for HIV-1 therapeutic intervention. Recently, we...

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Detalles Bibliográficos
Autores principales: Sakkhachornphop, Supachai, Thongkum, Weeraya, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439469/
https://www.ncbi.nlm.nih.gov/pubmed/26064960
http://dx.doi.org/10.1155/2015/853891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439469/
https://www.ncbi.nlm.nih.gov/pubmed/26064960
http://dx.doi.org/10.1155/2015/853891

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