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Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

Protein tyrosine phosphatase 1B (PTP1B) is an established therapeutic target for type 2 diabetes mellitus (T2DM) and obesity. The aim of this study was to investigate the inhibitory activity of Magnolia officinalis extract (ME) on PTP1B and its anti-T2DM effects. Inhibition assays and inhibition kin...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Wang, Yongsen, Fu, Xueqi, Chen, Yingli, Wang, Deli, Li, Wannan, Xing, Shu, Li, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439476/
https://www.ncbi.nlm.nih.gov/pubmed/26064877
http://dx.doi.org/10.1155/2015/139451