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Overweight in Mice and Enhanced Adipogenesis In Vitro Are Associated With Lack of the Hedgehog Coreceptor Boc

Obesity arises from a combination of genetic, environmental, and behavioral factors. However, the processes that regulate white adipose tissue (WAT) expansion at the level of the adipocyte are not well understood. The Hedgehog (HH) pathway plays a conserved role in adipogenesis, inhibiting fat forma...

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Detalles Bibliográficos
Autores principales: Lee, Hye-Jin, Jo, Shin-Bum, Romer, Anthony I., Lim, Hyo-Jeong, Kim, Min-Jung, Koo, Seung-Hoi, Krauss, Robert S., Kang, Jong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439556/
https://www.ncbi.nlm.nih.gov/pubmed/25576054
http://dx.doi.org/10.2337/db14-1017