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Foregut Exclusion Disrupts Intestinal Glucose Sensing and Alters Portal Nutrient and Hormonal Milieu

The antidiabetes effects of Roux-en-Y gastric bypass (RYGB) are well-known, but the underlying mechanisms remain unclear. Isolating the proximal small intestine, and in particular its luminal glucose sensors, from the nutrient stream has been proposed as a critical change, but the pathways involved...

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Detalles Bibliográficos
Autores principales: Pal, Atanu, Rhoads, David B., Tavakkoli, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439569/
https://www.ncbi.nlm.nih.gov/pubmed/25576062
http://dx.doi.org/10.2337/db14-1578