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Novel roles for protein disulphide isomerase in disease states: a double edged sword?

Protein disulphide isomerase (PDI) is a multifunctional redox chaperone of the endoplasmic reticulum (ER). Since it was first discovered 40 years ago the functions ascribed to PDI have evolved significantly and recent studies have recognized its distinct functions, with adverse as well as protective...

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Detalles Bibliográficos
Autores principales: Parakh, Sonam, Atkin, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439577/
https://www.ncbi.nlm.nih.gov/pubmed/26052512
http://dx.doi.org/10.3389/fcell.2015.00030