QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

The mitochondrial contact site and cristae junction (CJ) organizing system (MICOS) dynamically regulate mitochondrial membrane architecture. Through systematic proteomic analysis of human MICOS, we identified QIL1 (C19orf70) as a novel conserved MICOS subunit. QIL1 depletion disrupted CJ structure i...

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Detalles Bibliográficos
Autores principales: Guarani, Virginia, McNeill, Elizabeth M, Paulo, Joao A, Huttlin, Edward L, Fröhlich, Florian, Gygi, Steven P, Van Vactor, David, Harper, J Wade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439739/
https://www.ncbi.nlm.nih.gov/pubmed/25997101
http://dx.doi.org/10.7554/eLife.06265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439739/
https://www.ncbi.nlm.nih.gov/pubmed/25997101
http://dx.doi.org/10.7554/eLife.06265

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