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TGF-β Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma

Both transforming growth factor-β (TGF-β) and parathyroid hormone-related protein (PTHrP) regulate important cellular processes, such as apoptosis in the development of hepatocellular carcinoma. However, the mechanisms of regulation of PTHrP by TGF-β are largely unknown. We hypothesized that TGF-β r...

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Detalles Bibliográficos
Autores principales: Li, Hao, He, Guangchun, Yao, Hui, Song, Liujiang, Zeng, Liang, Peng, Xiaoning, Rosol, Thomas J., Deng, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439935/
https://www.ncbi.nlm.nih.gov/pubmed/26000041
http://dx.doi.org/10.7150/jca.10830