Hypothesis: Artifacts, Including Spurious Chimeric RNAs with a Short Homologous Sequence, Caused by Consecutive Reverse Transcriptions and Endogenous Random Primers

Recent RNA-sequencing technology and associated bioinformatics have led to identification of tens of thousands of putative human chimeric RNAs, i.e. RNAs containing sequences from two different genes, most of which are derived from neighboring genes on the same chromosome. In this essay, we redefine...

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Detalles Bibliográficos
Autores principales: Peng, Zhiyu, Yuan, Chengfu, Zellmer, Lucas, Liu, Siqi, Xu, Ningzhi, Liao, D. Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439942/
https://www.ncbi.nlm.nih.gov/pubmed/26000048
http://dx.doi.org/10.7150/jca.11997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439942/
https://www.ncbi.nlm.nih.gov/pubmed/26000048
http://dx.doi.org/10.7150/jca.11997

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