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Umbilical cord blood-derived dendritic cells loaded with BGC823 tumor antigens and DC-derived exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumor immunity in vitro and in vivo

BACKGROUND: Umbilical cord blood (UCB) is a rich source of hematopoietic stem cells and from which a significant number of dendritic cells (DCs) can be produced. But the therapeutic role of DCs and exosomes (EXO) generated from DCs is not fully elucidated. MATERIAL AND METHODS: The UCB-derived DCs w...

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Detalles Bibliográficos
Autores principales: Guan, Shasha, Li, Qianru, Liu, Pingping, Xuan, Xiaoyan, Du, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440031/
https://www.ncbi.nlm.nih.gov/pubmed/26155115
http://dx.doi.org/10.5114/ceji.2014.43713