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Δ10(E)-Sphingolipid Desaturase Involved in Fusaruside Mycosynthesis and Stress Adaptation in Fusarium graminearum

Sphingolipids are biologically important and structurally distinct cell membrane components. Fusaruside (1) is a 10,11-unsaturated immunosuppressive fungal sphingolipid with medical potentials for treating liver injury and colitis, but its poor natural abundance bottlenecks its druggability. Here, f...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Zhao, Guo Y., Fang, Wei, Xu, Qiang, Tan, Ren X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440215/
https://www.ncbi.nlm.nih.gov/pubmed/25994332
http://dx.doi.org/10.1038/srep10486