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Δ10(E)-Sphingolipid Desaturase Involved in Fusaruside Mycosynthesis and Stress Adaptation in Fusarium graminearum
Sphingolipids are biologically important and structurally distinct cell membrane components. Fusaruside (1) is a 10,11-unsaturated immunosuppressive fungal sphingolipid with medical potentials for treating liver injury and colitis, but its poor natural abundance bottlenecks its druggability. Here, f...
Autores principales: | Tian, Yuan, Zhao, Guo Y., Fang, Wei, Xu, Qiang, Tan, Ren X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440215/ https://www.ncbi.nlm.nih.gov/pubmed/25994332 http://dx.doi.org/10.1038/srep10486 |
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