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AURKA upregulation plays a role in fibroblast-reduced gefitinib sensitivity in the NSCLC cell line HCC827

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) have been used to treat non-small cell lung carcinoma (NSCLC) patients that have EGFR-activating mutations. EGFR-TKI monotherapy in most NSCLC patients with EGFR mutations who initially respond to EGFR-TKIs results in the...

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Detalles Bibliográficos
Autores principales: CHEN, JIA, LU, HUIQI, ZHOU, WANG, YIN, HUABIN, ZHU, LISHUANG, LIU, CHANG, ZHANG, PENGFEI, HU, HUIMIN, YANG, YILI, HAN, HUANXING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440218/
https://www.ncbi.nlm.nih.gov/pubmed/25634113
http://dx.doi.org/10.3892/or.2015.3764