Cargando…

Assessing dose–response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity

The fundamental principle in regulatory toxicology is that all chemicals are toxic and that the severity of effect is proportional to the exposure level. An ancillary assumption is that there are no effects at exposures below the lowest observed adverse effect level (LOAEL), either because no effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Zoeller, R Thomas, Vandenberg, Laura N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440251/
https://www.ncbi.nlm.nih.gov/pubmed/25971795
http://dx.doi.org/10.1186/s12940-015-0029-4