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Assessing dose–response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity
The fundamental principle in regulatory toxicology is that all chemicals are toxic and that the severity of effect is proportional to the exposure level. An ancillary assumption is that there are no effects at exposures below the lowest observed adverse effect level (LOAEL), either because no effect...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440251/ https://www.ncbi.nlm.nih.gov/pubmed/25971795 http://dx.doi.org/10.1186/s12940-015-0029-4 |