Diurnal and stress‐induced intra‐hippocampal corticosterone rise attenuated in 11β‐HSD1‐deficient mice: a microdialysis study in young and aged mice

11β‐Hydroxysteroid dehydrogenase type 1 (11β‐HSD1) locally regenerates active glucocorticoids from their inert forms thereby amplifying intracellular levels within target tissues including the brain. We previously showed greater increases in intra‐hippocampal corticosterone (CORT) levels upon Y‐maze...

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Detalles Bibliográficos
Autores principales: Yau, Joyce L. W., Noble, June, Kenyon, Christopher J., Ludwig, Mike, Seckl, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440343/
https://www.ncbi.nlm.nih.gov/pubmed/25614240
http://dx.doi.org/10.1111/ejn.12836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440343/
https://www.ncbi.nlm.nih.gov/pubmed/25614240
http://dx.doi.org/10.1111/ejn.12836

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