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Evolution and intelligent design in drug development

Sophisticated protein kinase networks, empowering complexity in higher organisms, are also drivers of devastating diseases such as cancer. Accordingly, these enzymes have become major drug targets of the twenty-first century. However, the holy grail of designing specific kinase inhibitors aimed at s...

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Detalles Bibliográficos
Autores principales: Agafonov, Roman V., Wilson, Christopher, Kern, Dorothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440380/
https://www.ncbi.nlm.nih.gov/pubmed/26052517
http://dx.doi.org/10.3389/fmolb.2015.00027