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Evolution and intelligent design in drug development
Sophisticated protein kinase networks, empowering complexity in higher organisms, are also drivers of devastating diseases such as cancer. Accordingly, these enzymes have become major drug targets of the twenty-first century. However, the holy grail of designing specific kinase inhibitors aimed at s...
Autores principales: | Agafonov, Roman V., Wilson, Christopher, Kern, Dorothee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440380/ https://www.ncbi.nlm.nih.gov/pubmed/26052517 http://dx.doi.org/10.3389/fmolb.2015.00027 |
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