Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells

Standard in vitro drug testing employs 2-D tissue culture plate systems to test anti-leukemic drugs against cell adhesion-mediated drug-resistant leukemic cells that harbor in 3-D bone marrow microenvironments. This drawback necessitates the fabrication of 3-D scaffolds that have cell adhesion-media...

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Detalles Bibliográficos
Autores principales: Nair, Maya S, Mony, Ullas, Menon, Deepthy, Koyakutty, Manzoor, Sidharthan, Neeraj, Pavithran, Keechilat, Nair, Shantikumar V, Menon, Krishnakumar N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440427/
https://www.ncbi.nlm.nih.gov/pubmed/26028971
http://dx.doi.org/10.2147/IJN.S80397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440427/
https://www.ncbi.nlm.nih.gov/pubmed/26028971
http://dx.doi.org/10.2147/IJN.S80397

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