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Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells
Standard in vitro drug testing employs 2-D tissue culture plate systems to test anti-leukemic drugs against cell adhesion-mediated drug-resistant leukemic cells that harbor in 3-D bone marrow microenvironments. This drawback necessitates the fabrication of 3-D scaffolds that have cell adhesion-media...
Autores principales: | Nair, Maya S, Mony, Ullas, Menon, Deepthy, Koyakutty, Manzoor, Sidharthan, Neeraj, Pavithran, Keechilat, Nair, Shantikumar V, Menon, Krishnakumar N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440427/ https://www.ncbi.nlm.nih.gov/pubmed/26028971 http://dx.doi.org/10.2147/IJN.S80397 |
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