Photodynamic Quenched Cathepsin Activity Based Probes for Cancer Detection and Macrophage Targeted Therapy

Elevated cathepsins levels and activities are found in several types of human cancer, making them valuable biomarkers for detection and targeting therapeutics. We designed small molecule quenched activity-based probes (qABPs) that fluoresce upon activity-dependent covalent modification, yielding cel...

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Detalles Bibliográficos
Autores principales: Ben-Nun, Yael, Merquiol, Emmanuelle, Brandis, Alexander, Turk, Boris, Scherz, Avigdor, Blum, Galia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440442/
https://www.ncbi.nlm.nih.gov/pubmed/26000057
http://dx.doi.org/10.7150/thno.10854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440442/
https://www.ncbi.nlm.nih.gov/pubmed/26000057
http://dx.doi.org/10.7150/thno.10854

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