Site-Specific Drug-Releasing Polypeptide Nanocarriers Based on Dual-pH Response for Enhanced Therapeutic Efficacy against Drug-Resistant Tumors

To enhance effective drug accumulation in drug-resistant tumors, a site-specific drug-releasing polypeptide system (PEG-Phis/Pasp-DOX/CA4) was exploited in response to tumor extracellular and intracellular pH. This system could firstly release the embedded tumor vascular inhibitor (CA4) to transient...

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Detalles Bibliográficos
Autores principales: Dong, Yaqiong, Yang, Jun, Liu, Hongmei, Wang, Tianyou, Tang, Suoqin, Zhang, Jinchao, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440445/
https://www.ncbi.nlm.nih.gov/pubmed/26000060
http://dx.doi.org/10.7150/thno.11821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440445/
https://www.ncbi.nlm.nih.gov/pubmed/26000060
http://dx.doi.org/10.7150/thno.11821

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