Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer

BACKGROUND: Iron binding, naturally occurring protein bovine lactoferrin (bLf) has attracted attention as a safe anti-cancer agent capable of inducing apoptosis. Naturally, bLf exists partially saturated (15-20%) with Fe(3+) however, it has been demonstrated that manipulating the saturation state ca...

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Detalles Bibliográficos
Autores principales: Gibbons, Jessica A., Kanwar, Jagat R., Kanwar, Rupinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440599/
https://www.ncbi.nlm.nih.gov/pubmed/25998617
http://dx.doi.org/10.1186/s12885-015-1441-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440599/
https://www.ncbi.nlm.nih.gov/pubmed/25998617
http://dx.doi.org/10.1186/s12885-015-1441-4

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