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Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila

LKB1 plays important roles in governing energy homeostasis by regulating AMP-activated protein kinase (AMPK) and other AMPK-related kinases, including the salt-inducible kinases (SIKs). However, the roles and regulation of LKB1 in lipid metabolism are poorly understood. Here we show that Drosophila...

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Detalles Bibliográficos
Autores principales: Choi, Sekyu, Lim, Dae-Sik, Chung, Jongkyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440640/
https://www.ncbi.nlm.nih.gov/pubmed/25996931
http://dx.doi.org/10.1371/journal.pgen.1005263