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Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth

We examined the thymoquinone induced inhibition of purified F(1) or membrane bound F(1)F(O) E. coli ATP synthase. Both purified F(1) and membrane bound F(1)F(O) were completely inhibited by thymoquinone with no residual ATPase activity. The process of inhibition was fully reversible and identical in...

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Detalles Bibliográficos
Autores principales: Ahmad, Zulfiqar, Laughlin, Thomas F., Kady, Ismail O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440651/
https://www.ncbi.nlm.nih.gov/pubmed/25996607
http://dx.doi.org/10.1371/journal.pone.0127802