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Cardiac β-Adrenoceptor Expression Is Reduced in Zucker Diabetic Fatty Rats as Type-2 Diabetes Progresses

OBJECTIVES: Reduced cardiac β-adrenoceptor (β-AR) expression and cardiovascular dysfunction occur in models of hyperglycemia and hypoinsulinemia. Cardiac β-AR expression in type-2 diabetes models of hyperglycemia and hyperinsulinemia, remain less clear. This study investigates cardiac β-AR expressio...

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Detalles Bibliográficos
Autores principales: Haley, James M., Thackeray, James T., Thorn, Stephanie L., DaSilva, Jean N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440709/
https://www.ncbi.nlm.nih.gov/pubmed/25996498
http://dx.doi.org/10.1371/journal.pone.0127581